Use of extended HR-HPV Genotyping in improving the Triage Strategy of 2019 ASCCP recommendations in Women with positive HR-HPV diagnosis and Simultaneous LSIL Cytology Results

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(HR‐HPV) and evaluate HPV‐DNA in subjects with abnormal cervical cytology results by using crowd‐based cervical cancer

The present study aimed to determine the geno‐ type and age distribution of high‐risk human papillomavirus (HR‐HPV) and evaluate HPV‐DNA in subjects with abnormal cervical cytology results by using crowd‐based cervical cancer screening cytology data. The Thinprep liquid‐based cytologic test (TCT) was performed from January 2013 to January 2014 in the permanent residents of Liaocheng (China) age...

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AIMS We investigated the effect of HR-HPV infection on the capacity of the cytokine network in whole blood cultures during carcinogenesis of cervical carcinoma. METHODS Thirty-nine women with moderate dysplasia, severe dysplasia, cervical carcinoma, or without dysplasia formed the study group. The control group consisted of 10 HR-HPV-negative women without CIN. Whole blood cultures were stimu...

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Combined CADM1/MAL methylation and cytology testing for colposcopy triage of high-risk HPV-positive women.

Primary screening for high-risk human papillomavirus (hrHPV) requires a triage protocol. Repeat cytology testing at baseline and after 6 to 12 months has emerged as a reasonable triage approach, but carries the risk of loss to follow-up. Repeat cytology testing may be omitted if cytology is supplemented with another, complementary triage test at baseline. In this study, the performance of combi...

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Triage of HR-HPV Positive Women with Minor Cytological Abnormalities: A Comparison of mRNA Testing, HPV DNA Testing, and Repeat Cytology Using a 4-Year Follow-Up of a Population-Based Study

OBJECTIVE Expression of the viral E6/E7 oncogenes of high-risk human papillomaviruses (HR-HPV) is necessary for malignant conversion and maintenance in cervical tissue. In order to determine whether HR-HPV E6/E7 mRNA testing more effectively predicts precancerous lesions and invasive cervical cancer than HR-HPV DNA testing, we aimed to compare triage using HR-HPV E6/E7 mRNA testing by APTIMA HP...

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ژورنال

عنوان ژورنال: Journal of Cancer

سال: 2021

ISSN: 1837-9664

DOI: 10.7150/jca.55826